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Global and United States Sartans Market Report & Forecast 2024-2031
1 Study Coverage
1.1 Sartans Product Introduction
1.2 Global Sartans Outlook 2017 VS 2022 VS 2028
1.2.1 Global Sartans Sales in US$ Million for the Year 2017-2028
1.2.2 Global Sartans Sales in Volume for the Year 2017-2028
1.3 United States Sartans Outlook 2017 VS 2022 VS 2028
1.3.1 United States Sartans Sales in US$ Million for the Year 2017-2028
1.3.2 United States Sartans Sales in Volume for the Year 2017-2028
1.4 Sartans Market Size, United States VS Global, 2017 VS 2022 VS 2028
1.4.1 The Market Share of United States Sartans in Global, 2017 VS 2022 VS 2028
1.4.2 The Growth Rate of Sartans Market Size, United States VS Global, 2017 VS 2022 VS 2028
1.5 Sartans Market Dynamics
1.5.1 Sartans Industry Trends
1.5.2 Sartans Market Drivers
1.5.3 Sartans Market Challenges
1.5.4 Sartans Market Restraints
1.6 Study Objectives
1.7 Years Considered
2 Market by Type
2.1 Sartans Market Segment by Type
2.1.1 Valsartan
2.1.2 Telmisartan
2.1.3 Losartan
2.1.4 Irbesartan
2.1.5 Azilsartan
2.1.6 Olmesartan
2.2 Global Sartans Market Size by Type
2.2.1 Global Sartans Sales in Value, by Type (2017, 2022 & 2028)
2.2.2 Global Sartans Sales in Volume, by Type (2017, 2022 & 2028)
2.2.3 Global Sartans Average Selling Price (ASP) by Type (2017, 2022 & 2028)
2.3 United States Sartans Market Size by Type
2.3.1 United States Sartans Sales in Value, by Type (2017, 2022 & 2028)
2.3.2 United States Sartans Sales in Volume, by Type (2017, 2022 & 2028)
2.3.3 United States Sartans Average Selling Price (ASP) by Type (2017, 2022 & 2028)
3 Market by Application
3.1 Sartans Market Segment by Application
3.1.1 Hypertension
3.1.2 Cardiovascular Diseases
3.1.3 Kidney Diseases
3.1.4 Other
3.2 Global Sartans Market Size by Application
3.2.1 Global Sartans Sales in Value, by Application (2017, 2022 & 2028)
3.2.2 Global Sartans Sales in Volume, by Application (2017, 2022 & 2028)
3.3.3 Global Sartans Average Selling Price (ASP) by Application (2017, 2022 & 2028)
3.3 United States Sartans Market Size by Application
3.3.1 United States Sartans Sales in Value, by Application (2017, 2022 & 2028)
3.3.2 United States Sartans Sales in Volume, by Application (2017, 2022 & 2028)
3.3.3 United States Sartans Average Selling Price (ASP) by Application (2017, 2022 & 2028)
4 Global Sartans Competitor Landscape by Company
4.1 Global Sartans Market Size by Company
4.1.1 Top Global Sartans Manufacturers Ranked by Revenue (2021)
4.1.2 Global Sartans Revenue by Manufacturer (2017-2022)
4.1.3 Global Sartans Sales by Manufacturer (2017-2022)
4.1.4 Global Sartans Price by Manufacturer (2017-2022)
4.2 Global Sartans Concentration Ratio (CR)
4.2.1 Sartans Market Concentration Ratio (CR) (2017-2022)
4.2.2 Global Top 5 and Top 10 Largest Manufacturers of Sartans in 2021
4.2.3 Global Sartans Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
4.3 Global Sartans Manufacturing Base Distribution, Product Type
4.3.1 Global Sartans Manufacturers, Headquarters and Distribution of Producing Region
4.3.2 Manufacturers Sartans Product Type
4.3.3 Date of International Manufacturers Enter into Sartans Market
4.4 Manufacturers Mergers & Acquisitions, Expansion Plans
4.5 United States Sartans Market Size by Company
4.5.1 Top Sartans Players in United States, Ranked by Revenue (2021)
4.5.2 United States Sartans Revenue by Players (2020, 2021 & 2022)
4.5.3 United States Sartans Sales by Players (2020, 2021 & 2022)
5 Global Sartans Market Size by Region
5.1 Global Sartans Market Size by Region: 2017 VS 2022 VS 2028
5.2 Global Sartans Market Size in Volume by Region (2017-2028)
5.2.1 Global Sartans Sales in Volume by Region: 2017-2022
5.2.2 Global Sartans Sales in Volume Forecast by Region (2023-2028)
5.3 Global Sartans Market Size in Value by Region (2017-2028)
5.3.1 Global Sartans Sales in Value by Region: 2017-2022
5.3.2 Global Sartans Sales in Value by Region: 2023-2028
6 Segment in Region Level & Country Level
6.1 North America
6.1.1 North America Sartans Market Size YoY Growth 2017-2028
6.1.2 North America Sartans Market Facts & Figures by Country (2017, 2022 & 2028)
6.1.3 U.S.
6.1.4 Canada
6.2 Asia-Pacific
6.2.1 Asia-Pacific Sartans Market Size YoY Growth 2017-2028
6.2.2 Asia-Pacific Sartans Market Facts & Figures by Region (2017, 2022 & 2028)
6.2.3 China
6.2.4 Japan
6.2.5 South Korea
6.2.6 India
6.2.7 Australia
6.2.8 Taiwan
6.2.9 Indonesia
6.2.10 Thailand
6.2.11 Malaysia
6.2.12 Philippines
6.3 Europe
6.3.1 Europe Sartans Market Size YoY Growth 2017-2028
6.3.2 Europe Sartans Market Facts & Figures by Country (2017, 2022 & 2028)
6.3.3 Germany
6.3.4 France
6.3.5 U.K.
6.3.6 Italy
6.3.7 Russia
6.4 Latin America
6.4.1 Latin America Sartans Market Size YoY Growth 2017-2028
6.4.2 Latin America Sartans Market Facts & Figures by Country (2017, 2022 & 2028)
6.4.3 Mexico
6.4.4 Brazil
6.4.5 Argentina
6.5 Middle East and Africa
6.5.1 Middle East and Africa Sartans Market Size YoY Growth 2017-2028
6.5.2 Middle East and Africa Sartans Market Facts & Figures by Country (2017, 2022 & 2028)
6.5.3 Turkey
6.5.4 Saudi Arabia
6.5.5 U.A.E
7 Company Profiles
7.1 Pfizer
7.1.1 Pfizer Corporation Information
7.1.2 Pfizer Description and Business Overview
7.1.3 Pfizer Sartans Sales, Revenue and Gross Margin (2017-2022)
7.1.4 Pfizer Sartans Products Offered
7.1.5 Pfizer Recent Development
7.2 Novartis
7.2.1 Novartis Corporation Information
7.2.2 Novartis Description and Business Overview
7.2.3 Novartis Sartans Sales, Revenue and Gross Margin (2017-2022)
7.2.4 Novartis Sartans Products Offered
7.2.5 Novartis Recent Development
7.3 Merck
7.3.1 Merck Corporation Information
7.3.2 Merck Description and Business Overview
7.3.3 Merck Sartans Sales, Revenue and Gross Margin (2017-2022)
7.3.4 Merck Sartans Products Offered
7.3.5 Merck Recent Development
7.4 Astra Zeneca
7.4.1 Astra Zeneca Corporation Information
7.4.2 Astra Zeneca Description and Business Overview
7.4.3 Astra Zeneca Sartans Sales, Revenue and Gross Margin (2017-2022)
7.4.4 Astra Zeneca Sartans Products Offered
7.4.5 Astra Zeneca Recent Development
7.5 Jhonson and Johnson
7.5.1 Jhonson and Johnson Corporation Information
7.5.2 Jhonson and Johnson Description and Business Overview
7.5.3 Jhonson and Johnson Sartans Sales, Revenue and Gross Margin (2017-2022)
7.5.4 Jhonson and Johnson Sartans Products Offered
7.5.5 Jhonson and Johnson Recent Development
7.6 Eli Lilly
7.6.1 Eli Lilly Corporation Information
7.6.2 Eli Lilly Description and Business Overview
7.6.3 Eli Lilly Sartans Sales, Revenue and Gross Margin (2017-2022)
7.6.4 Eli Lilly Sartans Products Offered
7.6.5 Eli Lilly Recent Development
7.7 Sanofi
7.7.1 Sanofi Corporation Information
7.7.2 Sanofi Description and Business Overview
7.7.3 Sanofi Sartans Sales, Revenue and Gross Margin (2017-2022)
7.7.4 Sanofi Sartans Products Offered
7.7.5 Sanofi Recent Development
7.8 Bristol-Myers Squibb
7.8.1 Bristol-Myers Squibb Corporation Information
7.8.2 Bristol-Myers Squibb Description and Business Overview
7.8.3 Bristol-Myers Squibb Sartans Sales, Revenue and Gross Margin (2017-2022)
7.8.4 Bristol-Myers Squibb Sartans Products Offered
7.8.5 Bristol-Myers Squibb Recent Development
7.9 Bayer
7.9.1 Bayer Corporation Information
7.9.2 Bayer Description and Business Overview
7.9.3 Bayer Sartans Sales, Revenue and Gross Margin (2017-2022)
7.9.4 Bayer Sartans Products Offered
7.9.5 Bayer Recent Development
7.10 GSK
7.10.1 GSK Corporation Information
7.10.2 GSK Description and Business Overview
7.10.3 GSK Sartans Sales, Revenue and Gross Margin (2017-2022)
7.10.4 GSK Sartans Products Offered
7.10.5 GSK Recent Development
7.11 Teva Pharmaceutical
7.11.1 Teva Pharmaceutical Corporation Information
7.11.2 Teva Pharmaceutical Description and Business Overview
7.11.3 Teva Pharmaceutical Sartans Sales, Revenue and Gross Margin (2017-2022)
7.11.4 Teva Pharmaceutical Sartans Products Offered
7.11.5 Teva Pharmaceutical Recent Development
8 Industry Chain and Sales Channels Analysis
8.1 Sartans Industry Chain Analysis
8.2 Sartans Key Raw Materials
8.2.1 Key Raw Materials
8.2.2 Sartans Distributors
8.3 Sartans Production Mode & Process
8.4 Sartans Sales and Marketing
8.4.1 Sartans Sales Channels
8.4.2 Sartans Distributors
8.5 Sartans Customers
9 Research Findings and Conclusion
10 Appendix
10.1 Research Methodology
10.1.1 Methodology/Research Approach
10.1.2 Data Source
10.2 Author Details
10.3 Disclaimer
List of Tables
Table 1. Sartans CAGR in Value, United States VS Global, 2017 VS 2022 VS 2028
Table 2. Sartans Market Trends
Table 3. Sartans Market Drivers
Table 4. Sartans Market Challenges
Table 5. Sartans Market Restraints
Table 6. Global Sartans Sales by Type: 2017 VS 2022 VS 2028 (US$ Million)
Table 7. United States Sartans Sales by Type: 2017 VS 2022 VS 2028 (US$ Million)
Table 8. Global Sartans Sales by Application: 2017 VS 2022 VS 2028 (US$ Million)
Table 9. United States Sartans Sales by Application: 2017 VS 2022 VS 2028 (US$ Million)
Table 10. Top Sartans Manufacturers in Global Market, Ranking by Revenue (2021)
Table 11. Global Sartans Revenue by Manufacturer, (US$ Million), 2017-2022
Table 12. Global Sartans Revenue Share by Manufacturer, 2017-2022
Table 13. Global Sartans Sales by Manufacturer, (K Units), 2017-2022
Table 14. Global Sartans Sales Share by Manufacturer, 2017-2022
Table 15. Global Sartans Price by Manufacturer (2017-2022) & (USD/Unit)
Table 16. Global Sartans Manufacturers Market Concentration Ratio (CR5 and HHI)
Table 17. Global Sartans by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Sartans as of 2021)
Table 18. Top Players of Sartans in Global Market, Headquarters and Distribution of Producing Region
Table 19. Manufacturers Sartans Product Type
Table 20. Date of International Manufacturers Enter into Sartans Market
Table 21. Manufacturers Mergers & Acquisitions, Expansion Plans
Table 22. Top Sartans Players in United States Market, Ranking by Revenue (2021)
Table 23. United States Sartans Revenue by Players, (US$ Million), 2020, 2021 & 2022
Table 24. United States Sartans Revenue Share by Players, 2020, 2021 & 2022
Table 25. United States Sartans Sales by Players, (K Units), 2020, 2021 & 2022
Table 26. United States Sartans Sales Share by Players, 2020, 2021 & 2022
Table 27. Global Sartans Market Size by Region (US$ Million): 2017 VS 2022 VS 2028
Table 28. Global Sartans Sales in Volume by Region (2017-2022) & (K Units)
Table 29. Global Sartans Sales in Volume Forecast by Region (2023-2028) & (K Units)
Table 30. Global Sartans Sales in Value by Region (2017-2022) & (US$ Million)
Table 31. Global Sartans Sales in Value Forecast by Region (2023-2028) & (US$ Million)
Table 32. North America Sartans Sales in Volume by Country (2017-2028) & (K Units)
Table 33. North America Sartans Sales in Value by Country (2017-2028) & (US$ Million)
Table 34. Asia Pacific Sartans Sales in Volume by Region (2017-2028) & (K Units)
Table 35. Asia Pacific Sartans Sales in Value by Region (2017-2028) & (US$ Million)
Table 36. Europe Sartans Sales in Volume by Country (2017-2028) & (K Units)
Table 37. Europe Sartans Sales in Value by Country (2017-2028) & (US$ Million)
Table 38. Latin America Sartans Sales in Volume by Country (2017-2028) & (K Units)
Table 39. Latin Americaa Sartans Sales in Value by Country (2017-2028) & (US$ Million)
Table 40. Middle East and Africa Sartans Sales in Volume by Country (2017-2028) & (K Units)
Table 41. Middle East and Africa Sartans Sales in Value by Country (2017-2028) & (US$ Million)
Table 42. Pfizer Corporation Information
Table 43. Pfizer Description and Business Overview
Table 44. Pfizer Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 45. Pfizer Sartans Product
Table 46. Pfizer Recent Development
Table 47. Novartis Corporation Information
Table 48. Novartis Description and Business Overview
Table 49. Novartis Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 50. Novartis Product
Table 51. Novartis Recent Development
Table 52. Merck Corporation Information
Table 53. Merck Description and Business Overview
Table 54. Merck Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 55. Merck Product
Table 56. Merck Recent Development
Table 57. Astra Zeneca Corporation Information
Table 58. Astra Zeneca Description and Business Overview
Table 59. Astra Zeneca Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 60. Astra Zeneca Product
Table 61. Astra Zeneca Recent Development
Table 62. Jhonson and Johnson Corporation Information
Table 63. Jhonson and Johnson Description and Business Overview
Table 64. Jhonson and Johnson Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 65. Jhonson and Johnson Product
Table 66. Jhonson and Johnson Recent Development
Table 67. Eli Lilly Corporation Information
Table 68. Eli Lilly Description and Business Overview
Table 69. Eli Lilly Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 70. Eli Lilly Product
Table 71. Eli Lilly Recent Development
Table 72. Sanofi Corporation Information
Table 73. Sanofi Description and Business Overview
Table 74. Sanofi Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 75. Sanofi Product
Table 76. Sanofi Recent Development
Table 77. Bristol-Myers Squibb Corporation Information
Table 78. Bristol-Myers Squibb Description and Business Overview
Table 79. Bristol-Myers Squibb Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 80. Bristol-Myers Squibb Product
Table 81. Bristol-Myers Squibb Recent Development
Table 82. Bayer Corporation Information
Table 83. Bayer Description and Business Overview
Table 84. Bayer Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 85. Bayer Product
Table 86. Bayer Recent Development
Table 87. GSK Corporation Information
Table 88. GSK Description and Business Overview
Table 89. GSK Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 90. GSK Product
Table 91. GSK Recent Development
Table 92. Teva Pharmaceutical Corporation Information
Table 93. Teva Pharmaceutical Description and Business Overview
Table 94. Teva Pharmaceutical Sartans Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022)
Table 95. Teva Pharmaceutical Product
Table 96. Teva Pharmaceutical Recent Development
Table 97. Key Raw Materials Lists
Table 98. Raw Materials Key Suppliers Lists
Table 99. Sartans Customers List
Table 100. Sartans Distributors List
Table 101. Research Programs/Design for This Report
Table 102. Key Data Information from Secondary Sources
Table 103. Key Data Information from Primary Sources
List of Figures
Figure 1. Sartans Product Picture
Figure 2. Global Sartans Revenue, (US$ Million), 2017 VS 2022 VS 2028
Figure 3. Global Sartans Market Size 2017-2028 (US$ Million)
Figure 4. Global Sartans Sales 2017-2028 (K Units)
Figure 5. United States Sartans Revenue, (US$ Million), 2017 VS 2022 VS 2028
Figure 6. United States Sartans Market Size 2017-2028 (US$ Million)
Figure 7. United States Sartans Sales 2017-2028 (K Units)
Figure 8. United States Sartans Market Share in Global, in Value (US$ Million) 2017-2028
Figure 9. United States Sartans Market Share in Global, in Volume (K Units) 2017-2028
Figure 10. Sartans Report Years Considered
Figure 11. Product Picture of Valsartan
Figure 12. Product Picture of Telmisartan
Figure 13. Product Picture of Losartan
Figure 14. Product Picture of Irbesartan
Figure 15. Product Picture of Azilsartan
Figure 16. Product Picture of Olmesartan
Figure 17. Global Sartans Market Share by Type in 2022 & 2028
Figure 18. Global Sartans Sales in Value by Type (2017-2028) & (US$ Million)
Figure 19. Global Sartans Sales Market Share in Value by Type (2017-2028)
Figure 20. Global Sartans Sales by Type (2017-2028) & (K Units)
Figure 21. Global Sartans Sales Market Share in Volume by Type (2017-2028)
Figure 22. Global Sartans Price by Type (2017-2028) & (USD/Unit)
Figure 23. United States Sartans Market Share by Type in 2022 & 2028
Figure 24. United States Sartans Sales in Value by Type (2017-2028) & (US$ Million)
Figure 25. United States Sartans Sales Market Share in Value by Type (2017-2028)
Figure 26. United States Sartans Sales by Type (2017-2028) & (K Units)
Figure 27. United States Sartans Sales Market Share in Volume by Type (2017-2028)
Figure 28. United States Sartans Price by Type (2017-2028) & (USD/Unit)
Figure 29. Product Picture of Hypertension
Figure 30. Product Picture of Cardiovascular Diseases
Figure 31. Product Picture of Kidney Diseases
Figure 32. Product Picture of Other
Figure 33. Global Sartans Market Share by Application in 2022 & 2028
Figure 34. Global Sartans Sales in Value by Application (2017-2028) & (US$ Million)
Figure 35. Global Sartans Sales Market Share in Value by Application (2017-2028)
Figure 36. Global Sartans Sales by Application (2017-2028) & (K Units)
Figure 37. Global Sartans Sales Market Share in Volume by Application (2017-2028)
Figure 38. Global Sartans Price by Application (2017-2028) & (USD/Unit)
Figure 39. United States Sartans Market Share by Application in 2022 & 2028
Figure 40. United States Sartans Sales in Value by Application (2017-2028) & (US$ Million)
Figure 41. United States Sartans Sales Market Share in Value by Application (2017-2028)
Figure 42. United States Sartans Sales by Application (2017-2028) & (K Units)
Figure 43. United States Sartans Sales Market Share in Volume by Application (2017-2028)
Figure 44. United States Sartans Price by Application (2017-2028) & (USD/Unit)
Figure 45. North America Sartans Sales in Volume Growth Rate 2017-2028 (K Units)
Figure 46. North America Sartans Sales in Value Growth Rate 2017-2028 (US$ Million)
Figure 47. U.S. Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 48. Canada Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 49. Europe Sartans Sales in Volume Growth Rate 2017-2028 (K Units)
Figure 50. Europe Sartans Sales in Value Growth Rate 2017-2028 (US$ Million)
Figure 51. Germany Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 52. France Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 53. U.K. Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 54. Italy Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 55. Russia Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 56. Asia-Pacific Sartans Sales in Volume Growth Rate 2017-2028 (K Units)
Figure 57. Asia-Pacific Sartans Sales in Value Growth Rate 2017-2028 (US$ Million)
Figure 58. China Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 59. Japan Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 60. South Korea Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 61. India Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 62. Australia Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 63. Taiwan Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 64. Indonesia Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 65. Thailand Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 66. Malaysia Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 67. Philippines Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 68. Latin America Sartans Sales in Volume Growth Rate 2017-2028 (K Units)
Figure 69. Latin America Sartans Sales in Value Growth Rate 2017-2028 (US$ Million)
Figure 70. Mexico Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 71. Brazil Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 72. Argentina Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 73. Middle East & Africa Sartans Sales in Volume Growth Rate 2017-2028 (K Units)
Figure 74. Middle East & Africa Sartans Sales in Value Growth Rate 2017-2028 (US$ Million)
Figure 75. Turkey Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 76. Saudi Arabia Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 77. U.A.E Sartans Sales in Value Growth Rate (2017-2028) & (US$ Million)
Figure 78. Sartans Value Chain
Figure 79. Sartans Production Process
Figure 80. Channels of Distribution
Figure 81. Distributors Profiles
Figure 82. Bottom-up and Top-down Approaches for This Report
Figure 83. Data Triangulation
Figure 84. Key Executives Interviewed
Please ask for List of Figures. Request Sample Report
Companies Included in Reports:
Pfizer Novartis Merck Astra Zeneca Jhonson and Johnson Eli Lilly Sanofi Bristol-Myers Squibb Bayer GSK Teva Pharmaceutical